Enhancement of metastases by antilymphocyte serum in allogeneic murine tumor system.

Further observations concerning effects of antilymphocyte serum on tumor growth: with special reference to allogeneic inhibition.

Reduction of antibody plaque-forming cells by allogeneic antilymphocyte serum.

Allogeneic mouse antilymphocyte serum effectively reduced the number of antibody plaque-forming cells after the natural antilytic property had been eliminated by dilution.

Antilymphocyte Serum and Allogeneic Inhibition1

Since 1958, when Snell (12) first reported that a trans planted C57BL lymphoma grew better in syngeneic C57BL mice than in Fj hybrids (C57BL X allogeneic strain), this phenomenon has been demonstrated with a variety of tumor lines. Such deficient tumor growth in hybrids was subse quently designated "allogenic inhibition" by the Hellströms (5—7). As a result of their extensive in vivo and in ...

Squamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic

Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...

Immunological Enhancement of Leukemia L1210 by Corynebacterium parvum in Allogeneic Mice1

We decided to investigate the immunological effects of C. parvum in an albogeneic murine tumor system. It was ex pected that C. parvum would have easily discernible adju vant effects that could be detected by in Vitro tests of cell mediated and humoral immunity. Instead, we found unex pectedly that at our dosage schedules C. parvum caused enhancement of tumor growth and a concomitant depres sio...